Derek T. Wei, Kayleigh N. Morrison, Gwendolyn M. Beacham, Erika Beyrent, Cyrus A. Habas, Ying Zhang, Laurence Florens, Gunther Hollopeter. ASPPs multimerize protein phosphatase 1 (2025) PLOS Genetics.
first posted to bioRxiv on May 16, 2025
Joe Chin-Hun Kuo, Marshall J. Colville, Michelle R. Sorkin, Jacky Lok Ka Kuo, Ling Ting Huang, Dana N. Thornlow, Gwendolyn M. Beacham, Gunther Hollopeter, Matthew P. DeLisa, Christopher A. Alabi*, Matthew J. Paszek*. Bio-orthogonal Glycan Imaging of Cultured Cells and Whole Animal C. elegans with Expansion Microscopy (2024). ASC Cent. Sci. *co-corresponding authors.
first posted to bioRxiv on February 2, 2024
Erika Beyrent, Derek T Wei*, Gwendolyn M Beacham*, Sangwoo Park, Jian Zheng, Matthew J Paszek, Gunther Hollopeter. Dimerization activates the Inversin complex in C. elegans (2024) Mol. Bio. Cell. *contributed equally.
first posted to bioRxiv on May 17, 2024
Edward A Partlow, Kevin S Cannon, Gunther Hollopeter*, Richard W Baker*. Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor complex for cargo internalization (2022). Nat. Struct. Mol. Biol. *co-corresponding authors.
Gwendolyn M Beacham, Derek T Wei*, Erika Beyrent*, Ying Zhang, Jian Zheng, Mari MK Camacho, Laurence Florens, Gunther Hollopeter. The C. elegans ASPP homolog APE-1 is a junctional protein phosphatase 1 modulator (2022). Genetics. *contributed equally.
first posted to bioRxiv on February 18, 2022
Gwendolyn M Beacham, Edward A Partlow, Gunther Hollopeter. Conformational regulation of AP1 and AP2 clathrin adaptor complexes (2019). Traffic 10:741-751.
Edward A Partlow, Richard W Baker*, Gwendolyn M Beacham, Joshua S Chappie, Andres E Leschziner*, Gunther Hollopeter*. A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex (2019). eLife 8:e50003. *co-corresponding authors.
first posted to bioRxiv on July 13, 2019
Gwendolyn M Beacham, Edward A Partlow, Jeffrey J Lange, Gunther Hollopeter. NECAPs are negative regulators of the clathrin adaptor complex (2018). eLife 10.7554/eLife.32242.
first posted to bioRxiv on September 22, 2017
SELECTED PUBLICATIONS FROM GUNTHER'S TRAINING:
Hollopeter G, Lange JJ, Zhang Y, Vu TV, Gu M, Ailion M, Lambie EJ, Slaughter BD, Unruh JR, Florens L, Jorgensen EM. The membrane-associated proteins FCHo and SGIP are allosteric activators of the AP2 clathrin adaptor complex (2014). eLife 10.7554/eLife.03648.
Liu Q, Hollopeter G, Jorgensen EM. Graded synaptic transmission at the Caenorhabditis elegans neuromuscular junction (2009). Proc. Natl. Acad. Sci. 106:10823-8.
Hollopeter G, Jantzen HM, Vincent D, Li G, England L, Ramakrishnan V, Yang RB, Nurden P, Nurden A, Julius D, Conley PB. Identification of the platelet ADP receptor targeted by antithrombotic drugs (2001). Nature 409: 202-207.
Erickson JC, Hollopeter G, Palmiter RD. Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y (1996). Science 274:1704-1707.
first posted to bioRxiv on May 16, 2025
Joe Chin-Hun Kuo, Marshall J. Colville, Michelle R. Sorkin, Jacky Lok Ka Kuo, Ling Ting Huang, Dana N. Thornlow, Gwendolyn M. Beacham, Gunther Hollopeter, Matthew P. DeLisa, Christopher A. Alabi*, Matthew J. Paszek*. Bio-orthogonal Glycan Imaging of Cultured Cells and Whole Animal C. elegans with Expansion Microscopy (2024). ASC Cent. Sci. *co-corresponding authors.
first posted to bioRxiv on February 2, 2024
Erika Beyrent, Derek T Wei*, Gwendolyn M Beacham*, Sangwoo Park, Jian Zheng, Matthew J Paszek, Gunther Hollopeter. Dimerization activates the Inversin complex in C. elegans (2024) Mol. Bio. Cell. *contributed equally.
first posted to bioRxiv on May 17, 2024
Edward A Partlow, Kevin S Cannon, Gunther Hollopeter*, Richard W Baker*. Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor complex for cargo internalization (2022). Nat. Struct. Mol. Biol. *co-corresponding authors.
Gwendolyn M Beacham, Derek T Wei*, Erika Beyrent*, Ying Zhang, Jian Zheng, Mari MK Camacho, Laurence Florens, Gunther Hollopeter. The C. elegans ASPP homolog APE-1 is a junctional protein phosphatase 1 modulator (2022). Genetics. *contributed equally.
first posted to bioRxiv on February 18, 2022
Gwendolyn M Beacham, Edward A Partlow, Gunther Hollopeter. Conformational regulation of AP1 and AP2 clathrin adaptor complexes (2019). Traffic 10:741-751.
Edward A Partlow, Richard W Baker*, Gwendolyn M Beacham, Joshua S Chappie, Andres E Leschziner*, Gunther Hollopeter*. A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex (2019). eLife 8:e50003. *co-corresponding authors.
first posted to bioRxiv on July 13, 2019
Gwendolyn M Beacham, Edward A Partlow, Jeffrey J Lange, Gunther Hollopeter. NECAPs are negative regulators of the clathrin adaptor complex (2018). eLife 10.7554/eLife.32242.
first posted to bioRxiv on September 22, 2017
SELECTED PUBLICATIONS FROM GUNTHER'S TRAINING:
Hollopeter G, Lange JJ, Zhang Y, Vu TV, Gu M, Ailion M, Lambie EJ, Slaughter BD, Unruh JR, Florens L, Jorgensen EM. The membrane-associated proteins FCHo and SGIP are allosteric activators of the AP2 clathrin adaptor complex (2014). eLife 10.7554/eLife.03648.
Liu Q, Hollopeter G, Jorgensen EM. Graded synaptic transmission at the Caenorhabditis elegans neuromuscular junction (2009). Proc. Natl. Acad. Sci. 106:10823-8.
Hollopeter G, Jantzen HM, Vincent D, Li G, England L, Ramakrishnan V, Yang RB, Nurden P, Nurden A, Julius D, Conley PB. Identification of the platelet ADP receptor targeted by antithrombotic drugs (2001). Nature 409: 202-207.
Erickson JC, Hollopeter G, Palmiter RD. Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y (1996). Science 274:1704-1707.